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Cleaved PARP Monoclonal Antibody (M4)

Product Specifications

Background

Poly (ADP-ribose) polymerase 1 (PARP1) Homo sapiens This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

Product Name Alternative

PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD (+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1

Gene ID

142

Swiss Prot

P09874

Cross Reactivity

Human

Clonality

Monoclonal

Source

Mouse

Applications

WB

Dilution

WB: 1:1000-3000

Buffer

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Molecular Weight

116,89

Storage Conditions

-20°C/1 year

Protein Weight

116,89

Available Sizes

Frequently Asked Questions

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