Cleaved PARP Monoclonal Antibody (Mix)
Product Specifications
Background
Poly (ADP-ribose) polymerase 1 (PARP1) Homo sapiens This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Product Name Alternative
PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD (+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Gene ID
142
Swiss Prot
P09874
Cross Reactivity
Human
Clonality
Monoclonal
Source
Mouse
Applications
IF/ICC; WB; IHC-p
Dilution
IF: 1:50-200 WB: 1:2000-5000 IHC 1:50-300
Buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Molecular Weight
116,89
Storage Conditions
-20°C/1 year
Protein Weight
116,89
Available Sizes
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