CD68 Monoclonal Antibody (6F3)
Product Specifications
Background
CD68 molecule (CD68) Homo sapiens This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Product Name Alternative
CD68; Macrosialin; Gp110; CD68
Gene ID
968
Swiss Prot
P34810
Cross Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Source
Mouse
Applications
IHC-P; IF/ICC
Dilution
WB 500-2000 1:200 IF 1:50-200
Buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Molecular Weight
37
Storage Conditions
-20°C/1 year
Protein Weight
37
Available Sizes
Curated Selection
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