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P44/42 MAPK (ERK1/2) Monoclonal Antibody (6C10)

Product Specifications

Background

Mitogen-activated protein kinase 3 (MAPK3) Homo sapiens The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]

Product Name Alternative

MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p

Gene ID

5594/5595

Swiss Prot

P27361/P28482

Cross Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Source

Mouse

Applications

WB; IHC-p; IF (paraffin section)

Dilution

WB 1:1000-2000, IHC 1:50-100

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

44,42

Storage Conditions

-20°C/1 year

Protein Weight

44,42

Available Sizes

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