PCNA Monoclonal Antibody (12D10)
Product Specifications
Background
Proliferating cell nuclear antigen (PCNA) Homo sapiens The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Product Name Alternative
PCNA; Proliferating cell nuclear antigen; PCNA; Cyclin
Gene ID
5111
Swiss Prot
P12004
Cross Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Source
Mouse
Applications
WB; IF/ICC; IHC-p
Dilution
WB: 1:5000 IHC: 1:200 IF 1:200
Buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Molecular Weight
29
Storage Conditions
-20°C/1 year
Protein Weight
29
Available Sizes
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