CD3E Monoclonal Antibody

Product Specifications

Background

CD3e molecule (CD3E) Homo sapiens The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Product Name Alternative

CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD antigen CD3e

Gene ID

916

Swiss Prot

P07766

Cross Reactivity

Human

Clonality

Monoclonal

Source

Mouse

Applications

WB; FCM; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.

Buffer

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage Conditions

-20°C/1 year