GAPDH Monoclonal Antibody (2B8)
Product Specifications
Background
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD) . The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri
Product Name Alternative
GAPDH; GAPD; CDABP0047; OK/SW-cl.12; Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH
Gene ID
2597
Swiss Prot
P04406
Cross Reactivity
Human; Rat; Mouse; Mk; Dg; Ch; Hamster; Rabbit; Pig; sheep; Insect; Yeast
Clonality
Monoclonal
Source
Mouse
Applications
WB; IF/ICC; IHC-p
Dilution
WB: 1:5000-20000 IHC: 1:200-300 IF 1:200
Buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Molecular Weight
37
Storage Conditions
-20°C/1 year
Protein Weight
37
Available Sizes
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