6-Amino-5-nitropyridin-2-one
6-Amino-5-nitropyridin-2-one is a pyridine base and used as a nucleobase of hachimoji DNA, in which it pairs with 5-aza-7-deazaguanine[1].
Product Specifications
CAS Number
[211555-30-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/6-Amino-5-nitropyridin-2-one.html
Purity
95.0
Solubility
H2O : 1.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=CC([N+]([O-])=O)=C(N)N1
Molecular Formula
C5H5N3O3
Molecular Weight
155.11
Precautions
H302, H315, H319, H335
References & Citations
[1]Hoshika S, et al. Hachimoji DNA and RNA: A genetic system with eight building blocks. Science. 2019 Feb 22;363 (6429) :884-887.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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