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6-Amino-5-nitropyridin-2-one

6-Amino-5-nitropyridin-2-one is a pyridine base and used as a nucleobase of hachimoji DNA, in which it pairs with 5-aza-7-deazaguanine[1].

Product Specifications

CAS Number

[211555-30-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/6-Amino-5-nitropyridin-2-one.html

Purity

95.0

Solubility

H2O : 1.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C=CC([N+]([O-])=O)=C(N)N1

Molecular Formula

C5H5N3O3

Molecular Weight

155.11

Precautions

H302, H315, H319, H335

References & Citations

[1]Hoshika S, et al. Hachimoji DNA and RNA: A genetic system with eight building blocks. Science. 2019 Feb 22;363 (6429) :884-887.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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