SDF1 [JJ09-20] Antibody
The stromal cell derived factor 1 (SDF1, CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1 isoforms (SDF1α and SDF1β) that have different properties and biological activities. Additional isoforms of SDF1 have been reported.
Product Specifications
Immunogen
Recombinant protein
Antibody Type
Primary Antibodies
Product Name Synonym
Available Sizes
Frequently Asked Questions
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