MEK3+MEK6 [JJ087-09] Antibody

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Product Specifications

Immunogen

Recombinant protein

Antibody Type

Primary Antibodies

Product Name Synonym

Dual specificity mitogen activated protein kinase kinase 6 antibody Dual specificity mitogen-activated protein kinase kinase 3 antibody MAP kinase kinase 3 antibody MAP kinase kinase 6 antibody map2k3 antibody MAP2K6 antibody MAPK/ERK kinase 3 antibody MAPK/ERK kinase 6 antibody MAPKK 3 antibody MAPKK 6 antibody MAPKK3 antibody MAPKK6 antibody MEK 3 antibody MEK 6 antibody Mitogen activated protein kinase kinase 3 antibody Mitogen activated protein kinase kinase 6 antibody MKK3 antibody MKK6 antibody MP2K3_HUMAN antibody PRKMK3 antibody PRKMK6 antibody Protein kinase, mitogen activated, kinase 6 (MAP kinase kinase 6) antibody SAPK kinase 2 antibody SAPKK 3 antibody SAPKK-2 antibody SAPKK2 antibody SAPKK3 antibody Stress activated protein kinase kinase 3 antibody Stress-activated protein kinase kinase 2 antibody