NUT Antibody

Disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t (15;19) (q14; p13) with BRD4 which produces a BRD4-NUT fusion protein. disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t (15;9) (q14; q34) with BRD3 which produces a BRD3-NUT fusion protein. PTM:Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export. Belongs to the FAM22 family. subcellular location:Shuttles between nucleus and cytoplasm. tissue specificity:Specifically expressed in testis.