RCC1 Antibody
Disease:Patients with Raynaud disease produce antibodies that bind to RCC1. Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Contains 7 RCC1 repeats. subcellular location:Becomes dispersed throughout the cytoplasm during mitosis.
Product Specifications
Immunogen
Synthetic peptide from human protein at AA range: 301-350
Antibody Type
Primary Antibodies
Product Name Synonym
RCC1 CHC1 antibody
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