CD249 Antibody

Catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide. cofactor:Binds 1 zinc ion per subunit. Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells. Belongs to the peptidase M1 family. subunit:Homodimer; disulfide-linked. tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.