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UBE4A Antibody

This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Product Specifications

Immunogen

Synthesized peptide derived from the N-terminal region of human UBE4A.

Antibody Type

Primary Antibodies

Product Name Synonym

UBE4A antibody; KIAA0126 antibody; Ubiquitin conjugation factor E4 A antibody

Available Sizes

Curated Selection

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