TRADD Antibody
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Product Specifications
Immunogen
The antiserum was produced against synthesized peptide derived from human TRADD. AA range:251-300
Antibody Type
Primary Antibodies
Product Name Synonym
TRADD antibody; Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody; TNFR1-associated DEATH domain protein antibody; TNFRSF1A-associated via death domain antibody
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