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TLE2 Antibody

Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Belongs to the WD repeat Groucho/TLE family. Contains 6 WD repeats. subunit:Homooligomer and heterooligomer with other family members. Binds LEF1, TCF7, TCF7L1, TCF7L2, UTY, HES1 and HES5. tissue specificity:In all tissues examined, mostly in heart, brain, and muscle.

Product Specifications

Immunogen

The antiserum was produced against synthesized peptide derived from human TLE2. AA range:211-260

Antibody Type

Primary Antibodies

Product Name Synonym

TLE2 antibody; Transducin-like enhancer protein 2 antibody; Enhancer of split groucho-like protein 2 antibody; ESG2 antibody

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