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SP-100 Antibody

This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) -SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.

Product Specifications

Immunogen

Synthesized peptide derived from SP-100 . at AA range: 250-330

Antibody Type

Primary Antibodies

Product Name Synonym

SP100 antibody; Nuclear autoantigen Sp-100 antibody; Lysp100b antibody; Nuclear dot-associated Sp100 protein antibody; Speckled 100 kDa antibody

Available Sizes

Frequently Asked Questions

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