Rabaptin-5α Antibody
Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity. Belongs to the rabaptin family. subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2.
Product Specifications
Immunogen
The antiserum was produced against synthesized peptide derived from human RABEP1. AA range:549-598
Antibody Type
Primary Antibodies
Product Name Synonym
RABEP1 antibody; RAB5EP antibody; RABPT5 antibody; RABPT5A antibody; Rab GTPase-binding effector protein 1 antibody; Rabaptin-4 antibody; Rabaptin-5 antibody; Rabaptin-5alpha antibody; Renal carcinoma antigen NY-REN-17 antibody
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