CYM 9484
CYM 9484 is a selective and highly potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM[1].
Product Specifications
CAS Number
[1383478-94-1]
UNSPSC
12352005
Hazard Statement
H315, H401
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cym-9484.html
Purity
98.68
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3CCN(C(NC4=CC=C(S(N(C)C)(=O)=O)C=C4)=S)CC3
Molecular Formula
C27H31N3O3S2
Molecular Weight
509.68
Precautions
H315, H401
References & Citations
[1] Mittapalli GK, et al. Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonists. Bioorg Med Chem Lett. 2012 Jun 15;22 (12) :3916-20.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NPY Y2 receptor
Available Sizes
Curated Selection
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