Thielavin A
Thielavin A is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin A specifically inhibits the conversion of arachidonic acid into prostaglandin H2. Thielavin A has no anti-inflammatory activity on intravenous injection or on oral administration[1].
Product Specifications
CAS Number
71950-66-8
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/thielavin-a.html
Purity
98.5
Solubility
10 mM in DMSO
Smiles
O=C(OC1=C(C)C(C)=C(C(O)=O)C(O)=C1C)C2=C(C)C(C)=C(OC(C3=C(C)C=C(O)C(C)=C3O)=O)C(C)=C2O
Molecular Formula
C29H30O10
Molecular Weight
538.54
References & Citations
[1]Kitahara N, et al. Thielavin A and B, new inhibitors of prostaglandin biosynthesis produced by Thielavia terricola. J Antibiot (Tokyo) . 1981;34 (12) :1562-1568.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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