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Thielavin A

Thielavin A is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin A specifically inhibits the conversion of arachidonic acid into prostaglandin H2. Thielavin A has no anti-inflammatory activity on intravenous injection or on oral administration[1].

Product Specifications

CAS Number

[71950-66-8]

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/thielavin-a.html

Purity

98.5

Solubility

10 mM in DMSO

Smiles

O=C(OC1=C(C)C(C)=C(C(O)=O)C(O)=C1C)C2=C(C)C(C)=C(OC(C3=C(C)C=C(O)C(C)=C3O)=O)C(C)=C2O

Molecular Formula

C29H30O10

Molecular Weight

538.54

References & Citations

[1]Kitahara N, et al. Thielavin A and B, new inhibitors of prostaglandin biosynthesis produced by Thielavia terricola. J Antibiot (Tokyo) . 1981;34 (12) :1562-1568.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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