ICG-Sulfo-OSu (sodium)

ICG-Sulfo-OSu sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[190714-28-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/icg-sulfo-osu-sodium.html

Purity

90.26

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=S(C(C1)C(N(OC(CCCCCN2/C(C(C)(C)C3=C2C=CC4=CC=CC=C34)=C\C=C\C=C\C=C\C5=[N+](CCCCS(=O)([O-])=O)C6=C(C7=CC=CC=C7C=C6)C5(C)C)=O)C1=O)=O)(O[Na])=O

Molecular Formula

C49H52N3NaO10S2

Molecular Weight

930.07

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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