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Park7 (DJ-1) Antibody

Product Specifications

Background

Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003) . Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011) .

Synonyms

CAP1 antibody, DJ-1 antibody, DJ1 antibody, DJ1 protein antibody, Epididymis secretory sperm binding protein Li 67p antibody, FLJ27376 antibody, FLJ34360 antibody, FLJ92274 antibody, HEL S 67p antibody, Oncogene DJ1 antibody, OTTHUMP00000001348 antibody, OTTHUMP00000001349 antibody, OTTHUMP00000001350 antibody, OTTHUMP00000001351 antibody, PARK7 antibody, PARK7_HUMAN antibody, Parkinson disease (autosomal recessive, early onset) 7 antibody, Parkinson disease protein 7 antibody, Parkinson protein 7 antibody, Protein DJ-1 antibody, SP22 antibody

Gene ID

117287

Swiss Prot

O88767

Host

Mouse

Cross Reactivity

Human, Mouse, Rat, Bovine

Target

Park7 (DJ-1)

Clonality

Monoclonal

Isotype

IgG1

Clone

4H4

Conjugation

Unconjugated

Source

Full length recombinant human Park7 expressed in and purified from E. coli.

Applications

WB, IHC

Purification

Purified by Protein G culture supernatant

Concentration

Lot Dependent

Dilution

WB (1:300-5000), IHC ()

Buffer

PBS + 10 mM NaN3.

Modification

Unmodified

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Specificity

Specific for endogenous levels of the ~21 kDa Park7 protein.

Gene ID URL

117287

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