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LAMP1 Antibody

Product Specifications

Background

Lysosomal Associated Membrane Protein1 (LAMP1) is a protein that is localized primarily in lysosomes but may also be present on late endosomes and the plasma membrane. LAMP1 antibodies are therefore widely used as lysosome markers. It has recently been suggested that lysosomes are activated in microglia in the progression of multiple system atrophy (MSA) and thus play a key role in its pathology (Makioka et al., 2012) .

Synonyms

CD107 antigen like family member A antibody, CD107 antigen-like family member A antibody, CD107a antibody, CD107a antigen antibody, LAMP 1 antibody, LAMP-1 antibody, LAMP1 antibody, LAMP1_HUMAN antibody, LAMPA antibody, LGP120 antibody, lgpA antibody, Lysosomal membrane glycoprotein 120KD antibody, Lysosomal Associated Membrane Protein 1 antibody, Lysosome associated membrane glycoprotein 1 antibody, Lysosome-associated membrane glycoprotein 1 antibody, Lysosome-associated membrane protein 1 antibody, OTTHUMP00000040663 antibody

Gene ID

3916

Swiss Prot

P11279

Host

Mouse

Cross Reactivity

Human

Target

LAMP1

Clonality

Monoclonal

Isotype

IgG1

Clone

5H6

Conjugation

Unconjugated

Source

Recombinant full length human LAMP1 expressed in and purified from E. coli.

Applications

WB, IHC

Purification

Purified by Protein G.

Concentration

Lot Dependent

Dilution

WB (1:300-5000), IHC ()

Buffer

PBS + 10 mM NaN3.

Modification

Unmodified

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Specificity

Specific for endogenous levels of the ~100 kDa LAMP1 protein.

Gene ID URL

3916

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