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FOX3 (NeuN) Antibody

Product Specifications

Background

FOX3, also known as NeuN and hexaribonucleotide binding protein 3, is a neuron-specific RNA binding nuclear protein involved in the regulation of pre-mRNA alternative splicing (Kim et al., 2009) . FOX3 dependent alternative splicing of Numb has recently been shown to play an important role in the progression of neuronal differentiation during vertebrate development (Kim et al., 2013) .

Synonyms

FLJ56884 antibody, FLJ58356 antibody, Fox-1 homolog C antibody, fox1 homolog C antibody, Fox 3 antibody, FOX3NeuN antibody, hexaribonucleotide binding protein 3 antibody, HRNBP3 antibody, NeuN antibody, NEUN antibody, neuronal nuclei antibody, Rbfox3 antibody, RFOX3_HUMAN antibody, RNA binding protein fox-1 homolog 3 antibody, RNA binding protein fox 1 homolog (C. elegans) 3 antibody

Gene ID

146713

Swiss Prot

A6NFN3

Host

Mouse

Cross Reactivity

Human, Mouse, Rat, Bovine

Target

FOX3 (NeuN)

Clonality

Monoclonal

Isotype

IgG2b

Clone

1B7

Conjugation

Unconjugated

Source

Recombinant protein taken from the N-terminus of human FOX3 expressed in and purified from E. Coli.

Applications

WB, IHC

Purification

Purified by Protein G.

Concentration

Lot Dependent

Dilution

WB (1:300-5000), IHC ()

Buffer

PBS + 50% glycerol and 5 mm NaN3

Modification

Unmodified

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Specificity

Specific for endogenous levels of the ~46/48 kDa FOX3 protein doublet.

Gene ID URL

146713

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