NPHS2 Monoclonal Antibody, PerCP Conjugated
Product Specifications
Background
Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.
Synonyms
Nephrosis 2, idiopathic, steroid resistant; NPHS2 gene; PDCN; Podocin; SRN1; PODO_HUMAN
Gene ID
7827
Swiss Prot
Q9NP85
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
NPHS2
Clonality
Monoclonal
Isotype
IgG
Conjugation
PerCP
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
482nm/677nm
Concentration
Lot Dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
7827
Curated Selection
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