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Doublin Monoclonal Antibody, PE-Cy5.5 Conjugated

Product Specifications

Background

Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration.

Synonyms

Doublecortex; DBCN; Dbct; DC; DCX; Doublin; Lis X; Lissencephalin X; Lissencephaly X linked; Lissencephaly X linked doublecortin; LISX; Neuronal migration protein doublecortin; SCLH; XLIS.

Gene ID

1641

Swiss Prot

O43602

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse, Rat

Target

Doublin

Clonality

Monoclonal

Isotype

IgG

Conjugation

PE-Cy5.5

Source

KLH conjugated synthetic peptide derived from human Doublecortin

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/694nm

Concentration

Lot Dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1641

Predicted Cross Reactivity

Human

Curated Selection

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