TRIM28 Recombinant Antibody, PerCP Conjugated
Product Specifications
Background
Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs) . Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me) ) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression.
Synonyms
E3 SUMO-protein ligase TRIM28; KRAB-associated protein 1; KAP-1; KRAB-interacting protein 1; KRIP-1; Nuclear corepressor KAP-1; KAP1; TF1B; RNF96; TIF1B; TRIM28.
Gene ID
10155
Swiss Prot
Q13263
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
TRIM28
Clonality
Recombinant
Isotype
IgG
Conjugation
PerCP
Source
KLH conjugated synthetic peptide derived from human TIF1 beta
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
482nm/677nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10155
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
abx250337-01 96 Tests
Human Procollagen Type I N-Terminal Propeptide (PINP) ELISA Kit
Ask
View Details abx250337-02 5x 96 Tests
Human Procollagen Type I N-Terminal Propeptide (PINP) ELISA Kit
Ask
View Details 
abx250337-03 10x 96 Tests
Human Procollagen Type I N-Terminal Propeptide (PINP) ELISA Kit
Ask
View Details 125704-HRP 100 µL
DDC (Aromatic-L-amino-acid Decarboxylase, AADC, DOPA Decarboxylase, DDC) (HRP)
Ask
View Details