TRAP1/HSP75 Recombinant Antibody, Cy5 Conjugated

Product Specifications

Background

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Synonyms

HSP75; HSP90L; Trap1.

Gene ID

10131

Swiss Prot

Q12931

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

TRAP1/HSP75

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human Hsp75

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10131

Available Sizes

Curated Selection

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