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TBX21 Recombinant Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

Lineage-defining transcription factor which initiates Th1 lineage development from naive Th precursor cells both by activating Th1 genetic programs and by repressing the opposing Th2 and Th17 genetic programs.Activates transcription of a set of genes important for Th1 cell function, including those encoding IFN-gamma and the chemokine receptor CXCR3. Induces permissive chromatin accessibilty and CpG methylation in IFNG.

Synonyms

T bet; T box 21; T PET; TBET; TBLYM; Tbx21; TPET; Transcription factor TBLYM.

Gene ID

30009

Swiss Prot

Q9UL17

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

Tbx21

Clonality

Recombinant

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic peptide derived from human TBX21

Applications

WB, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

30009

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