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Nesprin 3 Recombinant Antibody, FITC Conjugated

Product Specifications

Background

As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.

Synonyms

C14orf49; Nesp3; Nesprin 3; NET53; SYNE3.

Gene ID

161176

Swiss Prot

Q6ZMZ3

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

Nesprin 3

Clonality

Recombinant

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human Nesprin 3

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

161176

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