Phospho-RPS6KB2 (Ser370) Recombinant Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Phosphorylates specifically ribosomal protein S6.Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.
Synonyms
P70 beta; P70S6K2; p70S6Kb; Rps6kb2; S6K beta 2; S6K beta; S6K2; SRK; STK14B.
Gene ID
6199
Swiss Prot
Q9UBS0
Modification Site
Ser370
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
RPS6KB2
Clonality
Recombinant
Isotype
IgG
Conjugation
PE-Cy7
Source
KLH conjugated synthetic peptide derived from human p70 S6 kinase beta 2 around the phosphorylation site of S370
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6199
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