Phospho-RPS6KB2 (Ser370) Recombinant Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

Phosphorylates specifically ribosomal protein S6.Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.

Synonyms

P70 beta; P70S6K2; p70S6Kb; Rps6kb2; S6K beta 2; S6K beta; S6K2; SRK; STK14B.

Gene ID

6199

Swiss Prot

Q9UBS0

Modification Site

Ser370

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

RPS6KB2

Clonality

Recombinant

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic peptide derived from human p70 S6 kinase beta 2 around the phosphorylation site of S370

Applications

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6199

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