Phospho-RPS6KB1 (Thr421/Ser424) Recombinant Antibody, Cy3 Conjugated

Product Specifications

Background

Acts to integrate nutrient and growth factor signals in regulation of protein synthesis, cell proliferation, cell growth, cell cycle progression and cell survival. Downstream effector of the mTOR signaling pathway.

Synonyms

EC 2.7.11.1, KS6B1, P70-S6K, RPS6KB1, Ribosomal protein S6 kinase, Ribosomal protein S6 kinase, 70kDa, polypeptide 1, S6K, kinase p70S6K, p70-S6K.

Gene ID

6198

Swiss Prot

P23443

Modification Site

Thr421/Ser424

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Target

RPS6KB1

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human p70 S6 Kinase around the phosphorylation site of T421/S424

Applications

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6198

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