Phospho-RPS6KB1 (Thr421/Ser424) Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Acts to integrate nutrient and growth factor signals in regulation of protein synthesis, cell proliferation, cell growth, cell cycle progression and cell survival. Downstream effector of the mTOR signaling pathway.
Synonyms
EC 2.7.11.1, KS6B1, P70-S6K, RPS6KB1, Ribosomal protein S6 kinase, Ribosomal protein S6 kinase, 70kDa, polypeptide 1, S6K, kinase p70S6K, p70-S6K.
Gene ID
6198
Swiss Prot
P23443
Modification Site
Thr421/Ser424
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Target
RPS6KB1
Clonality
Recombinant
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human p70 S6 Kinase around the phosphorylation site of T421/S424
Applications
WB, IP
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IP (1-2ug)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
6198
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