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Phospho-PKD2 (Ser876) Recombinant Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress-induced NF-kappa-B activation, inhibition of HDAC7 transcriptional repression, signaling downstream of T-cell antigen receptor (TCR) and cytokine production, and plays a role in Golgi membrane trafficking, angiogenesis, secretory granule release and cell adhesion.

Synonyms

HSPC187; nPKC D2; PKD2; Prkd2; Protein kinase D2.

Gene ID

25865

Swiss Prot

Q9BZL6

Modification Site

Ser876

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PKD2

Clonality

Recombinant

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic peptide derived from human PKD2 around the phosphorylation site of S876

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

25865

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