Phospho-PKD2 (Ser876) Recombinant Antibody, APC Conjugated
Product Specifications
Background
Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress-induced NF-kappa-B activation, inhibition of HDAC7 transcriptional repression, signaling downstream of T-cell antigen receptor (TCR) and cytokine production, and plays a role in Golgi membrane trafficking, angiogenesis, secretory granule release and cell adhesion.
Synonyms
HSPC187; nPKC D2; PKD2; Prkd2; Protein kinase D2.
Gene ID
25865
Swiss Prot
Q9BZL6
Modification Site
Ser876
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
PKD2
Clonality
Recombinant
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human PKD2 around the phosphorylation site of S876
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
25865
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