Phospho-PKC delta (Thr507) Recombinant Antibody, PE Conjugated
Product Specifications
Background
Calcium-independent, phospholipid- and diacylglycerol (DAG) -dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses.
Synonyms
CVID9; KPCD; MAY1; nPKC delta; PCKd; PKC delta; PKCD; PKCdelta; PRKC D; PRKC delta; Prkcd.
Gene ID
5580
Swiss Prot
Q05655
Modification Site
Thr507
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
PKC delta
Clonality
Recombinant
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human PKC delta around the phosphorylation site of T507
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5580
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