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Phospho-MEK1 (Thr292) Recombinant Antibody, Cy7 Conjugated

Product Specifications

Background

Microtubule plus-end-directed kinetochore motor which plays an important role in chromosome congression, microtubule-kinetochore conjugation and spindle assembly checkpoint activation. Drives chromosome congression (alignment of chromosomes at the spindle equator resulting in the formation of the metaphase plate) by mediating the lateral sliding of polar chromosomes along spindle microtubules towards the spindle equator and by aiding the establishment and maintenance of connections between kinetochores and spindle microtubules.

Synonyms

Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K1; MEK-1; PRKMK1.

Gene ID

5604

Swiss Prot

Q02750

Modification Site

Thr292

Host

Rabbit

Cross Reactivity

Human

Target

MEK1

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human MEK1 around the phosphorylation site of T292

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5604

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