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Phospho-LRP6 (Ser1490) Recombinant Antibody, PerCP-Cy5.5 Conjugated

Product Specifications

Background

Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.

Synonyms

Low-density lipoprotein receptor-related protein 7.

Gene ID

4040

Swiss Prot

O75581

Modification Site

Ser1490

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

LRP6

Clonality

Recombinant

Isotype

IgG

Conjugation

PerCP-Cy5.5

Source

KLH conjugated synthetic peptide derived from human LRP6 around the phosphorylation site of S1490

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

482nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4040

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