Phospho-LRP6 (Ser1490) Recombinant Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.
Synonyms
Low-density lipoprotein receptor-related protein 7.
Gene ID
4040
Swiss Prot
O75581
Modification Site
Ser1490
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
LRP6
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human LRP6 around the phosphorylation site of S1490
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4040
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