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Phospho-LRP6 (Ser1490) Recombinant Antibody, APC Conjugated

Product Specifications

Background

Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.

Synonyms

Low-density lipoprotein receptor-related protein 7.

Gene ID

4040

Swiss Prot

O75581

Modification Site

Ser1490

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

LRP6

Clonality

Recombinant

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human LRP6 around the phosphorylation site of S1490

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4040

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