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Phospho-LRP6 (Ser1490) Recombinant Antibody

Product Specifications

Background

Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.

Synonyms

Low-density lipoprotein receptor-related protein 7.

Gene ID

4040

Swiss Prot

O75581

Modification Site

Ser1490

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

LRP6

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human LRP6 around the phosphorylation site of S1490

Applications

WB

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Phosphorylation

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

4040

Available Sizes

Frequently Asked Questions

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