Phospho-GLUT4 (Ser488) Recombinant Antibody, FITC Conjugated
Product Specifications
Background
Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.
Synonyms
Insulin-responsive; Glucose transporter GLUT 4; Glucose transporter type 4; Glucose transporter type 4 insulin responsive; GLUT4; Insulin responsive glucose transporter type 4; SLC2A4 ; Solute carrier family 2 member 4.
Gene ID
6517
Swiss Prot
P14672
Modification Site
Ser488
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
GLUT4
Clonality
Recombinant
Isotype
IgG
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from human GLUT4 around the phosphorylation site of S488
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6517
Curated Selection
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