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Phospho-GLUT4 (Ser488) Recombinant Antibody, Cy5 Conjugated

Product Specifications

Background

Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.

Synonyms

Insulin-responsive; Glucose transporter GLUT 4; Glucose transporter type 4; Glucose transporter type 4 insulin responsive; GLUT4; Insulin responsive glucose transporter type 4; SLC2A4 ; Solute carrier family 2 member 4.

Gene ID

6517

Swiss Prot

P14672

Modification Site

Ser488

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

GLUT4

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human GLUT4 around the phosphorylation site of S488

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6517

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