Phospho-eIF4EBP1/2/3 (Thr46/Thr46/Thr32) Recombinant Antibody, PE Conjugated
Product Specifications
Background
EIF4EBP1 is a member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs.
Synonyms
4EBP1; 4EBP2; 4EBP3; eIF4E binding protein 1; eIF4E binding protein 2; eIF4E binding protein 3; PHAS1.
Gene ID
1978
Swiss Prot
Q13541, Q13542, O60516
Modification Site
Thr46/Thr46/Thr32
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
EIF4EBP1/2/3
Clonality
Recombinant
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human 4E BP1 around the phosphorylation site of T46
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1978
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