Phospho-eIF4EBP1/2/3 (Thr46/Thr46/Thr32) Recombinant Antibody, Cy5 Conjugated

Product Specifications

Background

EIF4EBP1 is a member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs.

Synonyms

4EBP1; 4EBP2; 4EBP3; eIF4E binding protein 1; eIF4E binding protein 2; eIF4E binding protein 3; PHAS1.

Gene ID

1978

Swiss Prot

Q13541, Q13542, O60516

Modification Site

Thr46/Thr46/Thr32

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

EIF4EBP1/2/3

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human 4E BP1 around the phosphorylation site of T46

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1978

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