Phospho-STK4/3 (Thr183/Thr180) Recombinant Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Synonyms

KRS1; KRS2; MST1; MST2; STK3; STK4; YSK3.

Gene ID

6789

Swiss Prot

Q13043, Q13188

Modification Site

Thr183/Thr180

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

STK4/3

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic peptide derived from human STK4 around the phosphorylation site of T183

Applications

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6789

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