HN1 Recombinant Antibody, Cy5.5 Conjugated

Product Specifications

Background

Modulates negatively AKT-mediated GSK3B signaling.Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions.

Synonyms

ARM2; HN1; HN1A.

Gene ID

51155

Swiss Prot

Q9UK76

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

HN1

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy5.5

Source

KLH conjugated synthetic peptide derived from human JPT1

Applications

WB, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

675nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

51155

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